Free Test Nucleophilic substitution – NEET

Q1: Which of the following undergoes SN1 reaction most readily?

A. 1-chloro-2,2-dimethylpropane B. 1-chloropropane C. 1-chlorobutane D. 2-chloropropane

Q2: Which of the following is the best leaving group?

A. Cl⁻ B. OH⁻ C. NH₂⁻ D. H⁻

Q3: SN2 reactions are favored by:

A. Strong nucleophile B. Weak nucleophile C. Polar protic solvent D. Bulky substrate

Q4: Order of reactivity for SN2 reaction is:

A. methyl > 1° > 2° > 3° B. 3° > 2° > 1° > methyl C. 2° > 1° > 3° > methyl D. 1° > 2° > 3° > methyl

Q5: Which type of solvent favors SN1 reactions?

A. Polar protic B. Polar aprotic C. Non-polar D. Inert

Q6: What is the stereochemistry of SN2 reaction?

A. Inversion of configuration B. Retention of configuration C. Racemization D. No change

Q7: Which of the following is most reactive in SN1 reaction?

A. tert-butyl chloride B. ethyl chloride C. methyl chloride D. n-propyl chloride

Q8: SN2 mechanism involves:

A. One-step reaction B. Two-step reaction C. Three-step reaction D. No reaction

Q9: Which compound will not undergo SN1 easily?

A. Methyl chloride B. tert-Butyl chloride C. Benzyl chloride D. Allyl chloride

Q10: SN2 reactions occur fastest with:

A. CH₃Br B. CH₃CH₂Br C. CH₃CH₂CH₂Br D. CH₃CH₂CH₂CH₂Br

Q11: In SN1 reaction, intermediate formed is:

A. Carbocation B. Free radical C. Carbanion D. Nitrene

Q12: A polar aprotic solvent favors which reaction?

A. SN2 B. SN1 C. E1 D. E2

Q13: Which one of the following is least reactive in SN2 reaction?

A. tert-butyl bromide B. methyl bromide C. ethyl bromide D. propyl bromide

Q14: Which of the following undergoes inversion of configuration?

A. SN2 reaction B. SN1 reaction C. E1 reaction D. Electrophilic substitution

Q15: Which is better for SN1: H₂O or OH⁻?

A. H₂O B. OH⁻ C. Both equal D. Neither

Q16: Which is correct for SN2?

A. Rate ∝ [substrate][nucleophile] B. Rate ∝ [substrate] C. Rate ∝ [nucleophile] D. Rate independent of both

Q17: Which statement is true for SN1 reaction?

A. Intermediate is carbocation B. Nucleophile attacks immediately C. Backside attack occurs D. Always leads to inversion

Q18: Which halide shows highest reactivity towards SN2?

A. CH₃I B. CH₃Br C. CH₃Cl D. CH₃F

Quiz for Nucleophilic substitution