Quiz for SN1 & SN2

Q1: Which of the following favors SN1 mechanism?

A. Strong nucleophile and polar aprotic solvent B. Weak nucleophile and polar protic solvent C. Strong nucleophile and polar protic solvent D. Weak nucleophile and non-polar solvent

Q2: Which of the following is the correct order of SN1 reactivity?

A. 3° > 2° > 1° B. 1° > 2° > 3° C. 2° > 3° > 1° D. 3° > 1° > 2°

Q3: Which of the following statements is true about SN2 reactions?

A. It proceeds through a carbocation intermediate B. It leads to racemization of product C. It is a two-step reaction D. It results in inversion of configuration

Q4: What is the order of reactivity in SN2 reactions?

A. 3° > 2° > 1° B. 1° > 2° > 3° C. 2° > 3° > 1° D. 2° > 1° > 3°

Q5: Which condition favors SN2 mechanism?

A. 3° halide and weak nucleophile B. Polar protic solvent and 2° halide C. 1° halide and strong nucleophile in polar aprotic solvent D. 2° halide and water

Q6: Which of the following solvents favors SN1 mechanism?

A. Acetone B. DMSO C. Water D. THF

Q7: What is the stereochemical outcome of SN1 reaction?

A. Inversion B. Racemization C. Retention D. Meso compound

Q8: Which type of halide is most reactive in SN2 reaction?

A. 3° alkyl halide B. Allyl halide C. 1° alkyl halide D. Aryl halide

Q9: Which one proceeds via a backside attack?

A. SN1 B. Elimination C. SN2 D. Free radical substitution

Q10: Rate of SN1 reaction depends on:

A. Concentration of nucleophile only B. Concentration of alkyl halide only C. Both alkyl halide and nucleophile D. Neither

Q11: Rate of SN2 reaction is dependent on:

A. Only alkyl halide B. Only nucleophile C. Both alkyl halide and nucleophile D. Neither

Q12: Which of the following is not suitable for SN1 reaction?

A. 3° alkyl halide B. 2° alkyl halide C. 1° alkyl halide D. Allyl halide

Q13: Which type of product forms in SN1 reaction of chiral alkyl halide?

A. Only R isomer B. Only S isomer C. Racemate D. None

Q14: Which reaction occurs faster with methyl halide?

A. SN1 B. SN2 C. E1 D. Free radical

Q15: DMSO is best used in:

A. SN1 B. SN2 C. E1 D. E2

Q16: Which step is rate-determining in SN1?

A. Attack by nucleophile B. Loss of leaving group C. Formation of product D. Protonation

Q17: Which of the following does not affect SN1 rate?

A. Nature of solvent B. Carbocation stability C. Strength of nucleophile D. Leaving group ability

Q18: Which alkyl halide undergoes both SN1 and SN2?

A. 3° B. 2° C. 1° D. Methyl

Q19: What type of reaction gives Walden inversion?

A. SN1 B. SN2 C. E1 D. None

Q20: Which species will show highest rate in SN1?

A. CH3Cl B. CH3CH2Cl C. (CH3)3CCl D. CH2=CHCH2Cl